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Vitamin B12 (Cobalamin, Cyanocobalamin) Global Market

Vitamin B12 (Cobalamin, Cyanocobalamin) Global Market

Global Vitamin B12 (Cobalamin, Cyanocobalamin) Market Industry Research Report 2026

Explore detailed insights, trends, growth drivers, key players, and forecasts for the Global Vitamin B12 (Cobalamin, Cyanocobalamin) Market Industry Research Report 2026 market worldwide.

Pages: 220

Format: PDF

Date: 01-2026

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Global Vitamin B12 (Cobalamin, Cyanocobalamin) Market Report 2026–2036

Market Forecast

Chem Reports predicts that the Vitamin B12 (Cobalamin, Cyanocobalamin) market was valued at USD xxxx in 2025 and is expected to reach USD xxxx by 2036, growing at a CAGR of xx% globally during the forecast period 2026–2036.

Market Overview

The Global Vitamin B12 Market Report 2026 provides an extensive industry analysis of development components, patterns, flows, and market sizes. It evaluates present and past market values to forecast potential market performance between 2026–2036.

This study integrates both primary and secondary data sources, examining government policies, market environment, competitive landscape, historical data, current trends, technological innovation, upcoming technologies, and technical progress in related industries.

Impact of COVID-19

The COVID-19 outbreak in December 2019, declared a global public health emergency by the World Health Organization, significantly disrupted the Vitamin B12 market in 2020. Supply chain interruptions, reduced industrial activity, and delayed projects impacted demand, though recovery trends emerged as healthcare, nutraceutical, and pharmaceutical industries adapted to new operating conditions.

Market Segmentation

By Type

  • Cyanocobalamin Injection
  • Cyanocobalamin Oral
  • Cyanocobalamin Spray

By Application

  • Hospitals
  • Clinics

Regional Analysis

  • North America (U.S., Canada, Mexico): Strong demand in hospitals and clinics; regulatory oversight on pharmaceutical quality and safety.
  • Europe (Germany, U.K., France, Italy, Russia, Spain): Mature market with emphasis on healthcare and nutraceuticals; strict EU regulations drive innovation in sustainable production.
  • Asia-Pacific (China, India, Japan, Southeast Asia): Largest and fastest-growing region, supported by pharmaceutical manufacturing, nutraceutical expansion, and rising consumer health awareness.
  • South America (Brazil, Argentina): Emerging adoption in healthcare and clinical applications, supported by economic growth.
  • Middle East & Africa (Saudi Arabia, South Africa): Gradual growth with increasing investments in healthcare infrastructure and nutrition.

Key Players

  • Luitpold Pharmaceuticals (Daiichi Sankyo)
  • Bristol-Myers Squibb
  • Sanofi-Aventis
  • Jamieson
  • Teva (Actavis)
  • Merck
  • Mylan
  • Bayer HealthCare
  • Endo International
  • Pfizer
  • ANGELINI
  • Biological E
  • CCEPCD
  • Huaxin Pharmaceutical

These companies compete through production capacity, technological innovation, and distribution networks. Multinational firms dominate high-value pharmaceutical applications, while regional players serve cost-sensitive clinical and nutraceutical markets.

Global Vitamin B12 (Cobalamin, Cyanocobalamin) Market Intelligence Brief (2026–2036)

Short Description / Definition

Vitamin B12 (Cobalamin, Cyanocobalamin) is an essential water-soluble vitamin critical for red blood cell formation, neurological function, and DNA synthesis. It is widely used in pharmaceuticals, nutraceuticals, fortified foods, and clinical treatments. Available in injection, oral, and spray forms, Vitamin B12 is indispensable in treating deficiencies, supporting prenatal health, and enhancing overall wellness.

Regional Analysis

  • North America (U.S., Canada, Mexico): Strong demand in hospitals and clinics; regulatory oversight on pharmaceutical quality and safety.
  • Europe (Germany, U.K., France, Italy, Russia, Spain): Mature market with emphasis on healthcare and nutraceuticals; strict EU regulations drive innovation in sustainable production.
  • Asia-Pacific (China, India, Japan, Southeast Asia): Largest and fastest-growing region, supported by pharmaceutical manufacturing, nutraceutical expansion, and rising consumer health awareness.
  • South America (Brazil, Argentina): Emerging adoption in healthcare and clinical applications, supported by economic growth and rising middle-class consumption.
  • Middle East & Africa (Saudi Arabia, South Africa): Gradual growth with increasing investments in healthcare infrastructure and nutrition.

Segmentation Analysis

By Type:

  • Cyanocobalamin Injection
  • Cyanocobalamin Oral
  • Cyanocobalamin Spray

By Application:

  • Hospitals
  • Clinics

Key Players Analysis

  • Luitpold Pharmaceuticals (Daiichi Sankyo)
  • Bristol-Myers Squibb
  • Sanofi-Aventis
  • Jamieson
  • Teva (Actavis)
  • Merck
  • Mylan
  • Bayer HealthCare
  • Endo International
  • Pfizer
  • ANGELINI
  • Biological E
  • CCEPCD
  • Huaxin Pharmaceutical

Competitive landscape shows multinationals leading in pharmaceutical-grade innovation and distribution, while regional producers serve cost-sensitive clinical and nutraceutical markets.

Porter’s Five Forces

  • Threat of New Entrants: Moderate; production requires regulatory compliance and specialized synthesis.
  • Bargaining Power of Suppliers: Moderate; raw material volatility impacts costs.
  • Bargaining Power of Buyers: High; hospitals and clinics demand cost-effective, high-quality supply.
  • Threat of Substitutes: Low; Vitamin B12’s role as an essential vitamin is irreplaceable.
  • Industry Rivalry: High; strong competition among global leaders and regional producers.

SWOT Analysis

Strengths:

  • Essential vitamin with wide applicability in healthcare and nutrition
  • Strong demand across hospitals, clinics, and nutraceuticals

Weaknesses:

  • Dependence on chemical synthesis and raw materials
  • Price sensitivity in oral and spray formulations

Opportunities:

  • Growth in nutraceuticals and fortified foods
  • Expansion in Asia-Pacific and South America
  • Innovation in sustainable and bio-based production methods

Threats:

  • Regulatory scrutiny on pharmaceutical safety and supplements
  • Raw material price volatility
  • Competition from alternative supplements and delivery systems

Trend Analysis

  • Rising demand in clinical treatments for anemia and neurological disorders.
  • Expansion in nutraceuticals and fortified foods.
  • Growing use in prenatal and elderly healthcare.
  • Increasing focus on sustainable and bio-based production methods.

Drivers & Challenges

Drivers:

  • Expansion of healthcare and pharmaceutical industries
  • Rising consumer demand for fortified foods and supplements
  • Growth in preventive healthcare awareness globally

Challenges:

  • Regulatory scrutiny on pharmaceutical and nutraceutical safety
  • Dependence on cyclical raw material supply
  • Price volatility in chemical feedstocks

Value Chain Analysis

  • Upstream: Raw material sourcing and chemical synthesis.
  • Midstream: Production of injection, oral, and spray forms of Vitamin B12.
  • Downstream: Applications in hospitals, clinics, nutraceuticals, and fortified foods.
  • Support Activities: R&D, regulatory compliance, marketing, and distribution.

Quick Recommendations for Stakeholders

  • Manufacturers: Invest in sustainable production and expand into nutraceutical applications.
  • Investors: Focus on Asia-Pacific where demand growth is strongest.
  • Policy Makers: Encourage safe production practices and innovation in bio-based vitamins.
  • End-users (hospitals, clinics, nutraceutical firms): Secure long-term supply contracts with reliable producers.
  • New Entrants: Target niche applications in fortified foods and preventive healthcare.

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1. Market Overview of Vitamin B12 (Cobalamin, Cyanocobalamin)
    1.1 Vitamin B12 (Cobalamin, Cyanocobalamin) Market Overview
        1.1.1 Vitamin B12 (Cobalamin, Cyanocobalamin) Product Scope
        1.1.2 Market Status and Outlook
    1.2 Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Regions:
    1.3 Vitamin B12 (Cobalamin, Cyanocobalamin) Historic Market Size by Regions
    1.4 Vitamin B12 (Cobalamin, Cyanocobalamin) Forecasted Market Size by Regions
    1.5 Covid-19 Impact on Key Regions, Keyword Market Size YoY Growth
        1.5.1 North America
        1.5.2 East Asia
        1.5.3 Europe
        1.5.4 South Asia
        1.5.5 Southeast Asia
        1.5.6 Middle East
        1.5.7 Africa
        1.5.8 Oceania
        1.5.9 South America
        1.5.10 Rest of the World
    1.6 Coronavirus Disease 2019 (Covid-19) Impact Will Have a Severe Impact on Global Growth
        1.6.1 Covid-19 Impact: Global GDP Growth, 2019, 2020 and 2025 Projections
        1.6.2 Covid-19 Impact: Commodity Prices Indices
        1.6.3 Covid-19 Impact: Global Major Government Policy
2. Covid-19 Impact Vitamin B12 (Cobalamin, Cyanocobalamin) Sales Market by Type
    2.1 Global Vitamin B12 (Cobalamin, Cyanocobalamin) Historic Market Size by Type
    2.2 Global Vitamin B12 (Cobalamin, Cyanocobalamin) Forecasted Market Size by Type
    2.3 Cyanocobalamin Injection
    2.4 Cyanocobalamin Oral
    2.5 Cyanocobalamin Spray
3. Covid-19 Impact Vitamin B12 (Cobalamin, Cyanocobalamin) Sales Market by Application
    3.1 Global Vitamin B12 (Cobalamin, Cyanocobalamin) Historic Market Size by Application
    3.2 Global Vitamin B12 (Cobalamin, Cyanocobalamin) Forecasted Market Size by Application
    3.3 Hospitals
    3.4 Clinics
4. Covid-19 Impact Market Competition by Manufacturers
    4.1 Global Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity Market Share by Manufacturers
    4.2 Global Vitamin B12 (Cobalamin, Cyanocobalamin) Revenue Market Share by Manufacturers
    4.3 Global Vitamin B12 (Cobalamin, Cyanocobalamin) Average Price by Manufacturers
5. Company Profiles and Key Figures in Vitamin B12 (Cobalamin, Cyanocobalamin) Business
    5.1 Luitpold Pharmaceuticals
        5.1.1 Luitpold Pharmaceuticals Company Profile
        5.1.2 Luitpold Pharmaceuticals Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.1.3 Luitpold Pharmaceuticals Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.2 Luitpold Pharmaceuticals (Daiichi Sankyo)
        5.2.1 Luitpold Pharmaceuticals (Daiichi Sankyo) Company Profile
        5.2.2 Luitpold Pharmaceuticals (Daiichi Sankyo) Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.2.3 Luitpold Pharmaceuticals (Daiichi Sankyo) Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.3 Bristol-Myers Squibb
        5.3.1 Bristol-Myers Squibb Company Profile
        5.3.2 Bristol-Myers Squibb Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.3.3 Bristol-Myers Squibb Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.4 Sanofi-Aventis
        5.4.1 Sanofi-Aventis Company Profile
        5.4.2 Sanofi-Aventis Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.4.3 Sanofi-Aventis Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.5 Jamieson
        5.5.1 Jamieson Company Profile
        5.5.2 Jamieson Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.5.3 Jamieson Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.6 Teva (Actavis)
        5.6.1 Teva (Actavis) Company Profile
        5.6.2 Teva (Actavis) Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.6.3 Teva (Actavis) Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.7 Merck
        5.7.1 Merck Company Profile
        5.7.2 Merck Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.7.3 Merck Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.8 Mylan
        5.8.1 Mylan Company Profile
        5.8.2 Mylan Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.8.3 Mylan Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.9 Bayer HealthCare
        5.9.1 Bayer HealthCare Company Profile
        5.9.2 Bayer HealthCare Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.9.3 Bayer HealthCare Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.10 Endo International
        5.10.1 Endo International Company Profile
        5.10.2 Endo International Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.10.3 Endo International Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.11 Pfizer
        5.11.1 Pfizer Company Profile
        5.11.2 Pfizer Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.11.3 Pfizer Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.12 ANGELINI
        5.12.1 ANGELINI Company Profile
        5.12.2 ANGELINI Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.12.3 ANGELINI Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.13 Biological E
        5.13.1 Biological E Company Profile
        5.13.2 Biological E Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.13.3 Biological E Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.14 CCEPCD
        5.14.1 CCEPCD Company Profile
        5.14.2 CCEPCD Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.14.3 CCEPCD Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
    5.15 Huaxin Pharmaceutical
        5.15.1 Huaxin Pharmaceutical Company Profile
        5.15.2 Huaxin Pharmaceutical Vitamin B12 (Cobalamin, Cyanocobalamin) Product Specification
        5.15.3 Huaxin Pharmaceutical Vitamin B12 (Cobalamin, Cyanocobalamin) Production Capacity, Revenue, Price and Gross Margin
6. North America
    6.1 North America Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    6.2 North America Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    6.3 North America Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    6.4 North America Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
7. East Asia
    7.1 East Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    7.2 East Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    7.3 East Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    7.4 East Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
8. Europe
    8.1 Europe Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    8.2 Europe Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    8.3 Europe Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    8.4 Europe Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
9. South Asia
    9.1 South Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    9.2 South Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    9.3 South Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    9.4 South Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
10. Southeast Asia
    10.1 Southeast Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    10.2 Southeast Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    10.3 Southeast Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    10.4 Southeast Asia Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
11. Middle East
    11.1 Middle East Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    11.2 Middle East Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    11.3 Middle East Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    11.4 Middle East Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
12. Africa
    12.1 Africa Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    12.2 Africa Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    12.3 Africa Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    12.4 Africa Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
13. Oceania
    13.1 Oceania Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    13.2 Oceania Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    13.3 Oceania Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    13.4 Oceania Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
14. South America
    14.1 South America Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    14.2 South America Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    14.3 South America Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    14.4 South America Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
15. Rest of the World
    15.1 Rest of the World Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size
    15.2 Rest of the World Vitamin B12 (Cobalamin, Cyanocobalamin) Key Players in North America
    15.3 Rest of the World Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Type
    15.4 Rest of the World Vitamin B12 (Cobalamin, Cyanocobalamin) Market Size by Application
16 Vitamin B12 (Cobalamin, Cyanocobalamin) Market Dynamics
    16.1 Covid-19 Impact Market Top Trends
    16.2 Covid-19 Impact Market Drivers
    16.3 Covid-19 Impact Market Challenges
    16.4 Porter?s Five Forces Analysis
18 Regulatory Information
17 Analyst's Viewpoints/Conclusions
18 Appendix
    18.1 Research Methodology
        18.1.1 Methodology/Research Approach
        18.1.2 Data Source
    18.2 Disclaimer

Market Segmentation

By Type

  • Cyanocobalamin Injection
  • Cyanocobalamin Oral
  • Cyanocobalamin Spray

By Application

  • Hospitals
  • Clinics

Regional Analysis

  • North America (U.S., Canada, Mexico): Strong demand in hospitals and clinics; regulatory oversight on pharmaceutical quality and safety.
  • Europe (Germany, U.K., France, Italy, Russia, Spain): Mature market with emphasis on healthcare and nutraceuticals; strict EU regulations drive innovation in sustainable production.
  • Asia-Pacific (China, India, Japan, Southeast Asia): Largest and fastest-growing region, supported by pharmaceutical manufacturing, nutraceutical expansion, and rising consumer health awareness.
  • South America (Brazil, Argentina): Emerging adoption in healthcare and clinical applications, supported by economic growth.
  • Middle East & Africa (Saudi Arabia, South Africa): Gradual growth with increasing investments in healthcare infrastructure and nutrition.

Key Players

  • Luitpold Pharmaceuticals (Daiichi Sankyo)
  • Bristol-Myers Squibb
  • Sanofi-Aventis
  • Jamieson
  • Teva (Actavis)
  • Merck
  • Mylan
  • Bayer HealthCare
  • Endo International
  • Pfizer
  • ANGELINI
  • Biological E
  • CCEPCD
  • Huaxin Pharmaceutical

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